Serine/Arginine-rich protein family of splicing regulators: New approaches to study splice isoform functions
نویسندگان
چکیده
منابع مشابه
Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing.
We have recently identified an intronic polymorphic CA-repeat region in the human endothelial nitric oxide synthase (eNOS) gene as an important determinant of the splicing efficiency, requiring specific binding of hnRNP L. Here, we analyzed the position requirements of this CA-repeat element, which revealed its potential role in alternative splicing. In addition, we defined the RNA binding spec...
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The SR protein family of splicing factors: master regulators of gene expression.
The SR protein family comprises a number of phylogenetically conserved and structurally related proteins with a characteristic domain rich in arginine and serine residues, known as the RS domain. They play significant roles in constitutive pre-mRNA splicing and are also important regulators of alternative splicing. In addition they participate in post-splicing activities, such as mRNA nuclear e...
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The views, opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation. Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing...
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ژورنال
عنوان ژورنال: Plant Science
سال: 2019
ISSN: 0168-9452
DOI: 10.1016/j.plantsci.2019.02.017